Escherichia coli contamination of menstrual blood and effect of bacterial endotoxin on endometriosis.

نویسندگان

  • Khaleque Newaz Khan
  • Michio Kitajima
  • Koichi Hiraki
  • Naohiro Yamaguchi
  • Shigeru Katamine
  • Toshifumi Matsuyama
  • Masahiro Nakashima
  • Akira Fujishita
  • Tadayuki Ishimaru
  • Hideaki Masuzaki
چکیده

To test the hypothesis that bacterial contamination of menstrual blood could be a local biologic event in the development of endometriosis, menstrual blood was cultured and bacterial endotoxin was measured in menstrual blood and peritoneal fluid. Our results suggest that compared with control women, higher colony formation of Escherichia coli in menstrual blood and endotoxin levels in menstrual fluid and peritoneal fluid in women with endometriosis may promote Toll-like receptor 4-mediated growth of endometriosis.

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عنوان ژورنال:
  • Fertility and sterility

دوره 94 7  شماره 

صفحات  -

تاریخ انتشار 2010